Revolutionizing Cancer Care with Affordable, Advanced Proton Therapy
We will offer cancer patients access to affordable, advanced proton therapy by reducing the size and cost of existing devices via disruptive technology.
Proton Therapy
- Advanced Treatment compared to conventional x-ray radiotherapy
- Optimal radiation dose distribution
- Minimal side effects
- Fewer long-term complications
- Better quality of life
The Problem
Less than 2% of qualified patients receive proton therapy worldwide due to high cost and limited availability
Unaffordable
Treatment Cost in $ Thousands
X-ray Radiotherapy Proton Therapy
Inaccessible
Number of Units Worldwide
X-ray Radiotherapy Proton Therapy
Capital-intensive
Cost in $ Millions
X-ray Radiotherapy Proton Therapy
Our Solution
Current Single Room Proton System
Our GPTproton System
1/10
of the size
1/3
of the capital cost
Retrofit our device into existing X-ray radiotherapy room
Value Proposition

Patients
Gain significantly increased access to advanced proton treatments.

Physicians
Expand their treatment options with cutting-edge proton therapy, enabling more precise and personalized care.

Hospital
Accelerate return on investment and enhance patient care with lower-cost proton therapy adoption.

Insurance Company
Optimize long-term cost-effectiveness by covering proton therapy: reduce future claims through improved patient outcomes and fewer treatment-related complications.
Publications
The societal impact of ion beam therapy
T. Bortfeld, M. Viana, and S. Yan, “The societal impact of ion beam therapy”, Zeitschrift fur medizinische Physik, 31(2), p.102, May 2021.
Reassessment of the Necessity of the Proton Gantry
S. Yan, H-M. Lu, J. Flanz, J. Adams, A. Trofimov, and T. Bortfeld, “Reassessment of the necessity of the proton gantry: analysis of beam orientations from 4332 treatments at the Massachusetts General Hospital (MGH) proton center over the past 10 years”, International Journal of Radiation Oncology*Biology*Physics, Particle Therapy Special Edition, 95(1), 224–233, 2016.
Our journeys through the fascinating world of proton radiation therapy
T. Bortfeld and S. Yan, “Our journeys through the fascinating world of proton radiation therapy”, Medical Physics, Volume50, IssueS1, Pages 27-34, June 2023
Does the greater power of pencil beam scanning reduce the need for a proton gantry?
S. Yan, N. Depauw, J. Adams, B. L. Gorissen, H. A. Shih, J. Flanz, T. Bortfeld , H. Lu, “Does the greater power of pencil beam scanning reduce the need for a proton gantry? A study of head-and-neck and brain tumors”, Medical Physics, December 16, 2021.
Global democratisation of proton radiotherapy
S. Yan, T.A. Ngoma, W. Ngwa and T. Bortfeld, “Global democratisation of proton radiotherapy”, The Lancet Oncology, 24(6), pp.e245-e254, 2023.
Three ways to make proton therapy affordable
T. Bortfeld and J. Loeffler, “Three ways to make proton therapy affordable”. Nature. 549(7673):451-453, Sep 25, 2017.
Our Team

Thomas Bortfeld, PhD
- Chief of Physics Division, Radiation Oncology, MGH
- Andres Soriano Professor of Radiation Oncology, HMS
- Development of Intensity-Modulated Radiation Therapy (IMRT)
- > 30 million patients treated. 2.5 million QALY gained

Susu Yan, PhD
- Clinical medical physicist, Physics Division, Radiation Oncology, MGH
- Instructor, HMS
- 10 years experience in development of the project

Daniela Rus, PhD
- Robotics and computer scientist
- Andrew and Erna Viterbi Professor in the Department of Electrical Engineering and Computer Science (EECS), MIT
- Director of the MIT Computer Science and Artificial Intelligence Laboratory

Pit Arend
-
Chief Executive Officer
- B.Sc. in Mechanical Engineering and M.Sc. in Biomedical Engineering (Medical Physics) from ETH Zurich
- Acquired expertise in product development at Siemens Healthineers and MGH
- Contributed to innovations leading to patent filings

Clair Li
- Business Development Lead
- MPH candidate in Health Management at Harvard Chan
- Product strategist with specialty in consumer tech
- Innovation member at MESH Incubator focusing on market access and oncology innovation

Tianyi Zhou, PhD
- Business Operations Lead
- Ph.D. in Physics from Northeastern University
- Ph.D. researcher on medical imaging at Radiology, MGH
- Acquired experience in business development and market analysis in MedTech

Claude Biever
- Strategic Business Planning Lead
- M.Sc in Mechanical Engineering from ETH Zurich
- Acquired Experience in business development and market analysis through internships and consulting projects
- Expertise in product development of complex and innovative systems at the Paul Scherrer Institute

Fairlie Delbridge
- Harvard Advanced Leadership Initiative Fellow
- Harvard Innovation Lab Mentor
- Impact driven Angel Investor/Startup advisor in the USA & Australia
- Board Director of numerous Private and Social Enterprises
- Innovation & Impact focused venture builder

Helen Shih, MD
- World renowned expert in the treatment of tumors of the central nerve system
- Medical Director of Proton Therapy Centers, Massachusetts General Hospital
- Professor of Radiation Oncology, Harvard Medical School
- Founder, Shine360 Addiction
Only 106 proton centers are currently in operation worldwide
- High-income countries
- Middle-income countries
- Low-income countries
- Proton therapy centre
Contact Us
Whether you have a question about our services, need assistance, or just want to say hello, feel free to reach out to us using the contact information provided below.